Designed for industrial and embedded uses needing low power, strong performance, and dependable operation in difficult conditions, the MSI MS-CF16 V3.0 is a little Pico-ITX single board computer (SBC). Supported up to 16GB LPDDR5 onboard memory, it is built on Intel Alder Lake-N, Amston Lake, or Twin Lake CPUs and offers dual independent display outputs over HDMI and LVDS/eDP.
Including 1×2.5GbE LAN, 1xGbE LAN, 2xUSB 3.2, 2xUSB 2.0, 2xCOM ports (RS-232/422/485), GPIO, audio, SATA 3.0, and M.2 B and E key expansion options, the board offers rich connectivity. Making it ideal for fanless and tough applications, it has broad working temperature ranges—up to -40–70°C depending on CPU.
This Pico-ITX SBC is not similar to the other SBCs, such as the AAEON MIX-MTLD1, the UP Xtreme ARL, the Jetway MTX-MTH1, and other boards. Feel free to check those out for your reference.
MS-CF16 Industrial Pico-ITX SBC Specifications:
- SoC:
- Intel Alder Lake-N (N97, quad-core, 12W)
- Intel Twin Lake (N150, quad-core, 6W)
- Intel Amston Lake (Atom X7433RE, quad-core, 9W)
- GPU: Integrated Intel HD Graphics
- Memory: Up to 16GB LPDDR5-4800 onboard
- Storage:
- 1x SATA 3.0
- 1x M.2 B key (PCIe x1/SATA/USB)
- Video Output:
- HDMI (up to 3840×2160 @30Hz)
- LVDS/eDP (up to 1920×1200 @60Hz)
- Dual independent displays
- Audio: Realtek ALC897 codec
- Networking:
- 1x 2.5GbE (Realtek RTL8125)
- 1x 1GbE (Realtek RTL8111)
- USB:
- 2x USB 3.2 (1x Gen2, 1x Gen1)
- 2x USB 2.0
- Serial: 2x COM ports (RS-232/422/485 with 0V/5V/12V)
- GPIO: 16-bit (8x GPI, 8x GPO)
- Expansion:
- 1x M.2 B key 2242/3042
- 1x M.2 E key 2230
- Security: TPM 2.0 (Infineon SLB9672)
- Power Supply: 12V DC-in
- Dimension: 101 x 73 mm (Pico-ITX form factor)
- Operating Temperature:
- -10°C to 60°C (Alder/Twin Lake)
- -40°C to 70°C (Amston Lake)
- Weight: 0.30 kg
In terms of operating system, it supports Windows 10 IoT, Windows 11 IoT, and Linux (on request), thus designed to run applications in industrial automation, panel PCs, tablets, kiosks, embedded control systems and other edge computing solutions requiring compact size, reliability, and efficient performance.
The MSI’s official website does not mention pricing, but the MS-CF16 V3.0 Pico-ITX SBC is available in multiple SKUs depending on the processor option: Intel Alder Lake-N N97, Twin Lake N150, or Amston Lake Atom X7433RE, each paired with up to 16GB LPDDR5 memory and different operating temperature support. With optional extras including heatspreaders and wires, it is mostly aimed at industrial consumers and ought to be accessible through MSI’s embedded/industrial partners and distributors. Interested customers should contact MSI or authorised resellers for lead times and pricing, as expenses usually change depending on order quantity and configuration.



